CJC-1295 — Research Evidence & Community Data
Also known as: Modified GRF 1-29, GHRH analog, CJC-1295 DAC
Research & educational use only. This content is not medical advice. Consult a qualified healthcare professional before using any peptide compound.
What Is CJC-1295?
CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH 1-29), commonly studied alongside ghrelin-mimetic secretagogues. A DAC (drug affinity complex) variant is designed for an extended half-life. It is not FDA-approved and lacks published human efficacy randomized controlled trials; mechanistic data come largely from early pharmacology studies and animal models.
Is CJC-1295 FDA Approved?
CJC-1295 is not fda approved. It is treated as a research compound in the United States with no approved human clinical applications.
What Does the Research Show?
As of 2026, there are 0 human randomized controlled trials with a combined 0 subjects, and 12 animal model studies. Early pharmacokinetic and animal data describe elevated GH and IGF-1. No published human efficacy RCTs.
No linked evidence entries yet.
What Do Community Logs Show?
1 community protocol logs include CJC-1295. Browse community logs →
How Is CJC-1295 Used in Research?
Mechanism of action. Agonism of the GHRH receptor on pituitary somatotrophs, increasing growth hormone synthesis and release; the DAC version binds albumin to prolong action.
Half-life. Modified GRF 1-29 has a short half-life (minutes); the DAC variant is reported in days.
Storage. Lyophilized: store frozen, protect from light. Reconstituted: refrigerate 2-8C.
Reconstitution. Reconstituted with bacteriostatic water for research handling. Math only - not dosing guidance. See the reconstitution calculator — a math tool only, not dosing guidance.
What Does CJC-1295's Evidence Tier Mean?
CJC-1295 is rated Tier 4 · Theoretical. Mechanistic or theoretical basis only. Evidence tiers are a shorthand for how strong the human data is — Tier 1 reflects human randomized controlled trials, while lower tiers rest on observational, animal, or theoretical evidence. A higher tier means more confidence that observed effects are real and caused by the compound rather than by chance or bias. For how to weigh each tier, see our guide to understanding peptide evidence tiers.
How Do You Evaluate CJC-1295 Sourcing and Quality?
Because research-chemical CJC-1295 is unregulated, sourcing quality varies widely between sellers. Before trusting any supplier, check its reputation and enforcement history in the ranked list of trusted peptide sellers, and look for a batch-specific certificate of analysis (COA) showing third-party HPLC or LC-MS purity testing. Purity claims without a named lab, a batch number, and a method are marketing, not data. If you are reconstituting lyophilized material, the reconstitution calculator handles the arithmetic — it is a math tool only and not dosing guidance.
Where to Buy CJC-1295: Trusted & Verified Sellers
CJC-1295 is supplied by specialist research-chemical sellers rather than pharmacies, so where you buy it matters as much as what you buy. The sellers below have published moderator-approved third-party lab results for CJC-1295, ranked by overall reputation score. Always confirm a current batch-specific COA before purchasing.
No seller has published a lab result for CJC-1295 yet. Browse the ranked directory of trusted peptide sellers and check each one's lab testing and enforcement record before buying.
PeptidesHub does not sell CJC-1295 or facilitate transactions — this list is for research transparency only.
How Are Adverse Reactions to CJC-1295 Reported?
Structured adverse-event reports help the whole community spot safety signals early. You can browse approved reports on the adverse events page or submit one yourself. For a serious or life-threatening reaction, seek medical care and report it to FDA MedWatch.
Frequently Asked Questions
CJC-1295 is not fda approved. It is treated as a research compound in the United States.