AOD-9604 — Research Evidence & Community Data
Also known as: hGH fragment 176-191, AOD9604
Research & educational use only. This content is not medical advice. Consult a qualified healthcare professional before using any peptide compound.
What Is AOD-9604?
AOD-9604 is a synthetic fragment of human growth hormone (the C-terminal 176-191 region) originally developed as an anti-obesity agent. Clinical trials for weight loss did not demonstrate significant efficacy versus placebo, and it was not approved as a drug; it has since been marketed in some regions as a food or cosmetic ingredient. Evidence for body-composition or repair benefits in humans is weak.
Is AOD-9604 FDA Approved?
AOD-9604 is not fda approved. It is treated as a research compound in the United States with no approved human clinical applications.
What Does the Research Show?
As of 2026, there are 3 human randomized controlled trials with a combined 800 subjects, and 15 animal model studies. Human trials exist but the pivotal obesity program did not show significant weight loss versus placebo.
Phase 2 obesity trials failed to show significant weight loss versus placebo, ending development as an anti-obesity drug.
No linked evidence entries yet.
What Do Community Logs Show?
No community logs include AOD-9604 yet. Browse community logs →
How Is AOD-9604 Used in Research?
Mechanism of action. Proposed effects on lipid metabolism derived from the GH C-terminal fragment, without the full GH receptor activity.
Half-life. Short plasma half-life.
Storage. Lyophilized: store frozen. Reconstituted: refrigerate 2-8C.
Reconstitution. Reconstituted with bacteriostatic water for research handling. Math only - not dosing guidance. See the reconstitution calculator — a math tool only, not dosing guidance.
What Does AOD-9604's Evidence Tier Mean?
AOD-9604 is rated Tier 2 · Observational. Supported by human observational or clinical reports. Evidence tiers are a shorthand for how strong the human data is — Tier 1 reflects human randomized controlled trials, while lower tiers rest on observational, animal, or theoretical evidence. A higher tier means more confidence that observed effects are real and caused by the compound rather than by chance or bias. For how to weigh each tier, see our guide to understanding peptide evidence tiers.
How Do You Evaluate AOD-9604 Sourcing and Quality?
Because research-chemical AOD-9604 is unregulated, sourcing quality varies widely between sellers. Before trusting any supplier, check its reputation and enforcement history in the ranked list of trusted peptide sellers, and look for a batch-specific certificate of analysis (COA) showing third-party HPLC or LC-MS purity testing. Purity claims without a named lab, a batch number, and a method are marketing, not data. If you are reconstituting lyophilized material, the reconstitution calculator handles the arithmetic — it is a math tool only and not dosing guidance.
Where to Buy AOD-9604: Trusted & Verified Sellers
AOD-9604 is supplied by specialist research-chemical sellers rather than pharmacies, so where you buy it matters as much as what you buy. The sellers below have published moderator-approved third-party lab results for AOD-9604, ranked by overall reputation score. Always confirm a current batch-specific COA before purchasing.
No seller has published a lab result for AOD-9604 yet. Browse the ranked directory of trusted peptide sellers and check each one's lab testing and enforcement record before buying.
PeptidesHub does not sell AOD-9604 or facilitate transactions — this list is for research transparency only.
How Are Adverse Reactions to AOD-9604 Reported?
Structured adverse-event reports help the whole community spot safety signals early. You can browse approved reports on the adverse events page or submit one yourself. For a serious or life-threatening reaction, seek medical care and report it to FDA MedWatch.
Frequently Asked Questions
AOD-9604 is not fda approved. It is treated as a research compound in the United States.