AOD-9604: the fat-loss peptide that failed its trials
Research & educational use only. This content is not medical advice. Consult a qualified healthcare professional before using any peptide compound.
AOD-9604 is a useful cautionary tale. It is a fragment of human growth hormone (the 176-191 region) that was developed specifically as an anti-obesity drug, and the pivotal phase 2 trials did not show significant weight loss versus placebo.
Development as a drug ended, and it later resurfaced as a food or cosmetic ingredient in some regions. When people market it for fat loss now, they are ignoring that it already failed the exact test that matters.