KPV: the anti-inflammatory tripeptide from alpha-MSH
Research & educational use only. This content is not medical advice. Consult a qualified healthcare professional before using any peptide compound.
KPV (lysine-proline-valine) is the C-terminal tripeptide of alpha-MSH, studied mostly for anti-inflammatory activity in gut and skin models. The preclinical rationale around NF-kB modulation is interesting.
As with most things here, the catch is that it is preclinical: animal and cell models, no published human efficacy RCTs. Worth following for inflammatory research, but the human case is unproven.
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