Humanin and longevity signaling: where is the human data?
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Humanin keeps showing up in longevity discussions for its cytoprotective and neuroprotective signaling. From what I can find, though, the evidence is entirely preclinical and mechanistic. Is there any human efficacy data I am missing?
If not, this seems like a clear Tier 4 situation: a compelling biological story with essentially no controlled human results behind the aging claims.